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Mephedrone: Short or Long term effects.

Forums Drugs Research Chemicals Mephedrone: Short or Long term effects.

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  • welcome to pv shine on :love:

    interesting you mention 3-mmc, i’d not heard of it before. seems it was indeed a more potent contaminant in earlier mephe whilst that was legal.
    some interesting info on 3-mmc referenced on bluelight: (RC’s) 3-MMC (3-Methylmethcathinone)

    3-mmc is not present in today’s mephe even when pure (BL say) due to different synthesis paths from different sources. probably a good thing since it is apparently even worse for your heart than 4-mmc (the notional content of mephedrine of course).

    Yeah i’d heard about 3-mmc being a contaminant in 4-mmc before. Pretty much all of what you said.
    Apparently it’s because the majority of mephe. was made in China before the ban, then the precursors were banned there so it is now made in India (Apparently with a cleaner synth, but less potent product)
    Fuck knows, in the end its all bad for you so..

    Shortterm- a fucking good time, nystagmus, bruxia, vasoconstriction
    Longterm – memory loss (improved since abstinence), chest pains (improved since abstinence), social anxiety, general anxiety (improved vastly since abstinence) paranoia (improved vastly since abstinence)

    I don’t know if this is correct, so someone correct me if it isn’t, but i believe that it is particularly bad for anxiety issues/mental health issues in general due to the fact that it rapes your brain of dopamine?

    not sure about the precise science/chemistry stuff but comparing the effects it had on me and my friends with the effects of pills/MDMA in 1991 when it first came out and other stimulants I would say what happens is the bad mental stuff will happen with both, but it appears far quicker with mephedrone compared to pills/MDMA or amfetamines..

    I found with MDMA the comedown/tiredness was more gradual whereas with cathinones it went from on top of the world to feeling proper paranoid and anxious within a space of half an hour.

    Auch wenn du am Abgrund stehst, und gar nichts mehr verstehst,
    wachen Engel über dich, halten dich im Licht und lassen dich nie fallen.

    Imo MDMA comedown is easier to deal with, i can handle being depressed after use for maybe a day or so.
    For me, with mephe, i get the crushing depression followed by days/weeks of skatty paranoia.
    I do agree though, the effects wear off very suddenly especially when snorted.

    As far as i’m aware, 4-MMC is both more serotonegenic and dopagenic (If those are the correct terms)
    It has also been suggested that as it is a cousin of cathinone, it may (may being the key word) cause impotence with long term use.

    @Deezl 514074 wrote:

    I don’t know if this is correct, so someone correct me if it isn’t, but i believe that it is particularly bad for anxiety issues/mental health issues in general due to the fact that it rapes your brain of dopamine?

    yes i believe so. i don’t have the references to hand but i’ll try to remember to find and post. analyses (of what i don’t recall) indicate it potentiates and depletes dopamine on an equivalence with mdma whereas for serotonin it, like other cathinones, is only 30% as effective as the amphetamine derived equivalent.

    [edit] so given that most people seem to take 3 times as much typically (500mg to 1g) as mdma i guess it is bad for dopamine.

    Actually i’d read that it was more powerful serotonin wise compared to MDMA, i’ll try find all my sources, just a case of diggin’ em up.
    I think having real low levels of dopamine can cause schizophrenia (obv. over a long period of time) which could obviously be an issue with mephe.

    500mg-1g is actually a very conservative dose.. Or atleast that’s without a tolerance, which doesn’t take long to develop and doesn’t seem to ever fade. Personally i’ve seen people do 8gs, but i don’t know how they can even do it to themselves, its sad. It’s an evil evil drug once the initial honeymoon period is over, sucks you in with no comedown, great effects, leaves you mentally ruined after a while.

    Also, seizures are an issue – many hardcore mephheads will eventually get seizures, people in my area are dropping like flys with them now after repeatedly binging for 1-2yrs. Don’t know if its directly caused by the drug or treating your body like shit though.

    hey well i can’t find the links i was thinking of. i did find the bluelight page that said mephe was 3x on serotonin compared to mdma as you mention. maybe i was thinking of methylone as the bookmarks are all in the same folder. if i find anything more i’ll post back here.

    It makes sense. I also believe the psychological addiction is made stronger by the extreme dopamine deprevation.. brain assosciates mephedrone with massive amounts of dopamine & good times, so wants you to take more.
    I couldn’t find my links either but i think i’m just being lazy anyway, a lot of what i know is from BL.

    bl is 51 times more informative than wiki
    “really?”
    dogs bollocks

    any old twat can post on bluelight, for all you know you’re reading a 14 year olds posts.

    that be so but as with anything you gotta check the referencces they mention. of course anecdotal reports are ok with suitable skepticism and you can discount FOAFs and gauge SWIMS (not that folk swim on bl but ykwim). i view these sites as a conduit to enlightenment not necessarily an answer in themselves 😉

    arrr that it be

    Exactly.. i don’t read every post and take it as fact, i use it as a reference and seek more information that either supports or disputes it.
    But a lot of the decent information that is posted has sources & studies etc. anyway

    Well Im no chemist or Doctor so can only post from the experience of me and my mates which consists of several years of taking MDMA every Friday night (and sometimes Saturdays to ) in late teens to mid 20s, ranging from 1-3 pills plus often a g of wizz, then 2-3 years of taking Drone, again Friday nights though not every week like the pilling days, more like every 2nd or 3rd weekend……………

    Always had good times when on good stuff ( though a quite a few disappointments on bunk rip offs ), always needed at least a day to recover ( though a large part of that is due to lack of sleep ), never had any sign of seizures or chest pains or schizophrenia.

    MDMA – always left me drained for a couple of days afterwars, day after taking would be a w/o smoking tons of weed and just vegging out, following 1-2 would just be tired and lacking motivation to do anything.

    Drone – Same on day afterwards, maybe more severe though that could be more down to being older when I took it than I was on MDMA, but recovered faster after a day in bed, though that could be due to lack of weed available.

    I do generally have a poor memory, but dont know if thats down to taking LSD in early teens, MDMA & wizz, Drone, or smoking weed for 20 years, or combination of all, or just natural deterioration with age. Paranoia is hard to say, when carrying certainly worried about being caught, and very few people I worked with ever knew what I did on weekends…. but I dont think thats paranoia, thats just being cautious since I didnt want to get busted or lose my job.

    Addiction, on drone & MDMA none, like it, want it sometimes, but never felt I needed it. Tobacco I am physically addicted to, and for a long time I would say I was psychologically addicted to weed, got very stressed when I couldnt get any and would never want to get back to the point where I was smoking it every day, or even every week.

    NOT saying Drone or MDMA or any other drug/chem is safe or harmless, they all carry risk of and do damage…. but comparatively I would say occasional use in sensible doses is safer and less harmful than tobacco or alcohol, far more enjoyable, and being in clubs/events full of pillheads you are far less likely to get into trouble than drinking clubs.

    IMO The biggest long term effects – missed out on career advancement & messed up relationships due to wanting to keep partying forever instead of putting the proper time/effort into these things

    a healthy human, whether or not they take drugs does not seriously deteriorate with age until into their late 50s or early 60s.

    The comedown is harsher on drone than MDMA, but for any drug the only reason us older users notice it more is because we have more responsibilities and the comedown/recovery period impacts on this. In our younger days someone else was picking up the pieces after us for things we lunched out (parents/co-workers/employers) – also being snappy on comedowns when you are normally a good person does freak out even those close to us.

    IMO this is as much (or the real?) reason why drugs control continues more so than the silly politicians..

    Auch wenn du am Abgrund stehst, und gar nichts mehr verstehst,
    wachen Engel über dich, halten dich im Licht und lassen dich nie fallen.

    @General Lighting 515548 wrote:

    a healthy human, whether or not they take drugs does not seriously deteriorate with age until into their late 50s or early 60s.

    The comedown is harsher on drone than MDMA, but for any drug the only reason us older users notice it more is because we have more responsibilities and the comedown/recovery period impacts on this. In our younger days someone else was picking up the pieces after us for things we lunched out (parents/co-workers/employers) – also being snappy on comedowns when you are normally a good person does freak out even those close to us.

    IMO this is as much (or the real?) reason why drugs control continues more so than the silly politicians..

    I would agree on the responsibilities bit, hence why I was only ever a weekend user ( Mostly Friday nights ) to allow time to recover before returning to work, and for most people ( as with my friends ) they stopped taking stuff because they had kids, you simply cant mix drugs/comedowns with looking after little people. Nothing to do with health or legalities, just natural parental instincts.

    As for others picking up the pieces in youth, not in my case, I was working and paying my way a week after leaving school, within a year made homeless, forced to buy a flat as I couldnt afford to rent, and had to work ever since else I would be homeless again, so all through my pilling days I had the same responsibilities I do now.

    But one the severity of comedowns as I said I always found Drone more severe but shorter, whereas MDMA was less severe but lasted longer.

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Forums Drugs Research Chemicals Mephedrone: Short or Long term effects.