OLDCHAP HERE Hi guys
my names Jim,
a bit about myself, i am still a hardcore raver even though im getting on a bit. fuck it way i see it you only live once. heavily into my DnB raving and also Tech,Deep House. i also DJ when i get the chance mainy at home but do play at raves ocassionally. if i could choose one thing in this world to never stop it would be the rave/party scene as you just cant fucking beat it!!!!
Here These studies investigated the absorption and metabolic conversion of lisdexamfetamine dimesylate (LDX), a prodrug stimulant that requires conversion to d-amphetamine for activity. Oral absorption of LDX was assessed in rat portal and jugular blood, and perfusion of LDX into isolated intestinal segments of anesthetized rats was used to assess regional absorption. Carrier-mediated transport of LDX was investigated in Caco-2 cells and Chinese hamster ovary (CHO) cells expressing human peptide transporter-1 (PEPT1). LDX metabolism was studied in rat and human tissue homogenates and human blood fractions. LDX was approximately10-fold higher in portal blood versus systemic blood. LDX and d-amphetamine were detected in blood following perfusion of the rat small intestine but not the colon. Transport of LDX in Caco-2 cells had permeability apparently similar to cephalexin and was reduced with concurrent PEPT1 inhibitor. Affinity for PEPT1 was also demonstrated in PEPT1-transfected CHO cells. LDX metabolism occurred primarily in whole blood (rat and human), only with red blood cells. Slow hydrolysis in liver and kidney homogenates was probably due to residual blood. The carrier-mediated absorption of intact LDX, likely by the high-capacity PEPT1 transporter, and subsequent metabolism to d-amphetamine in a high-capacity system in blood (ie, red blood cells) may contribute to the consistent, reproducible pharmacokinetic profile of LDX
Are these liberty caps If found them by a riverside today and was just wondering if these wr the real deal or impostors ? Also I know the last pic is not a cap but is it a deadly one?.
walter hannan i live in melbourne australia a friend arrived in london at 3.30 this arvo shes staying at a hotel in paddington she would like to get some nice smoke if anybody can point the right direction would be appeceated ever in my neck of the woods glad to return the favor
Hello Hey. I'm just introducing myself. My name is James. I'm really just here to find girls to have skype sex with. Based on my searches, I'm going to assume I'm not unique in that regard.
My skype id is bob.lahblah
52 yr old newbie My Due to my recent long career in the military I was unable to 'dabble' in certain things! We are tested randomly approx twice a year sometimes more. Now I'm 'free' I can experiment:smile:. My first 'taste' was with a 36 yr old experienced user who introduced me to this amazing new world. We had the most amazing sex in the few months before she 'drugged' me. (That's not fair because I was very willing!).
My first experience was when she brought some coke to one of our weekend hotel meets. I had a couple of lines before we went for a lunchtime drink. The conversation in the pub was much more open and I was feeling very confident and I could tell she was as well. Back to the room and a few more lines... Unbelievable! A marathon session followed :-) I won't go into detail but can if u want? Haha. Just pm me :wink:
Our next weekend she brought some ecstasy pills. We had a meal and a few drinks in the hotel bar and we both popped a pill mid-meal (her advice). Anyway, half hour after the meal we were sat chatting and FUCKINHELL! Boom. What a fantastic feeling, she started giggling and said...your eyes! You're coming up ain't ya? I really can't begin to explain the beautiful feelings I had, she wanted to go outside for a smoke so I went along. It was a very pleasant summers night, we walked around the hotel. I noticed the street lights looked fantastic, I was buzzing, laughing, smiling. I clearly remember walking along with my hands in the air and shouting. 'I'm free look at the colours'. The events in our room after were incredible...
I have to disappear for a bit now but will come back and tell you more of our 18 month relationship. I will be requesting some advice and guidance on certain substances and hope to share your knowledge to help me with some decisions about the future.
Regards.....Michael x
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