never been depressed as such but too much K has always made me as sick as a dog (indeed I once k-holed, slumped in a corner and came round to find on either side of me a border collie and an old cat (both female), who were the pets of a girl who lived at the place I was visting, and they were actually guarding me as they would one of their own puppies or kittens who had been suddenly taken ill..
